Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724808 | 0.90 | MEN1 (0.53) | MEN1NPC1RAB9AKMT2AGAA | |
| SCHEMBL5037571 | 0.86 | MAPK1 (0.63) | MEN1NPC1RAB9AKMT2AMAPT | |
| SCHEMBL9724978 | 0.86 | KMT2A (0.52) | MEN1NPC1RAB9AKMT2AGAA | |
| SCHEMBL9724923 | 0.86 | RAB9A (0.50) | BACE1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9724970 | 0.84 | MAPT (0.55) | MEN1NPC1RAB9AKMT2AMAPT | |
| SCHEMBL9724833 | 0.83 | LMNA (0.54) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL9724950 | 0.82 | ALDH1A1 (0.54) | MEN1NPC1RAB9AKMT2AMAPT | |
| SCHEMBL9724968 | 0.82 | KMT2A (0.65) | NPC1RAB9AKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9724801 | 0.80 | HPGD (0.56) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL9724811 | 0.79 | MME (0.65) | MEN1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |