Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724829 | 0.90 | BACE1 (0.54) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL9724833 | 0.89 | LMNA (0.54) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL5037571 | 0.89 | MAPK1 (0.63) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL9724978 | 0.89 | KMT2A (0.52) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL9724923 | 0.89 | RAB9A (0.50) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL9724967 | 0.86 | MAPT (0.67) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL9724970 | 0.86 | MAPT (0.55) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL9724950 | 0.85 | ALDH1A1 (0.54) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL9724968 | 0.85 | KMT2A (0.65) | KMT2ANPC1RAB9APOLBMAPT | |
| SCHEMBL9724847 | 0.85 | PKM (0.65) | MEN1KMT2ANPC1RAB9AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | claimed |
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |