Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724808 | 0.86 | MEN1 (0.53) | MAPTKMT2AMEN1TP53ALDH1A1 | |
| SCHEMBL9724967 | 0.86 | MAPT (0.67) | MAPTKMT2AMEN1TP53ALDH1A1 | |
| SCHEMBL9724786 | 0.84 | DDX3X (0.51) | MAPTKMT2AMEN1TP53ALDH1A1 | |
| SCHEMBL9724829 | 0.84 | BACE1 (0.54) | MAPTKMT2AMEN1TP53HIF1A | |
| SCHEMBL9724859 | 0.81 | ALDH1A1 (0.60) | MAPTKMT2AMEN1TP53ALDH1A1 | |
| SCHEMBL9724920 | 0.81 | RAB9A (0.67) | MAPTKMT2AMEN1ALDH1A1NLRP3 | |
| SCHEMBL9724839 | 0.81 | MME (0.55) | MAPTKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL9724978 | 0.77 | KMT2A (0.52) | MAPTKMT2AMEN1TP53ALDH1A1 | |
| SCHEMBL9724833 | 0.77 | LMNA (0.54) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL9724838 | 0.77 | ATM (0.51) | MAPTKMT2AMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |