Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724957 | 0.88 | CYP1A2 (0.41) | CTSLCTSBCYP1A2GPR132HDAC8 | |
| SCHEMBL7286971 | 0.83 | PSMB5 (0.51) | RENCTSLCTSBCTSS | |
| SCHEMBL7286963 | 0.83 | PSMB5 (0.51) | RENCTSLCTSBCTSS | |
| SCHEMBL7285504 | 0.83 | CTSS (0.50) | RENCTSLCTSBCTSSHDAC8 | |
| SCHEMBL7285491 | 0.83 | CTSS (0.50) | RENCTSLCTSBCTSSHDAC8 | |
| SCHEMBL7295646 | 0.82 | CYP1A2 (0.43) | TSHRALDH1A1HPGDALOX15TDP1 | |
| SCHEMBL7295654 | 0.82 | CYP1A2 (0.43) | TSHRALDH1A1HPGDALOX15TDP1 | |
| SCHEMBL7442083 | 0.81 | REN (0.40) | RENTDP1CTSLCTSBCTSS | |
| SCHEMBL7286303 | 0.80 | TACR1 (0.54) | CTSLCTSBCTSS | |
| SCHEMBL7286309 | 0.80 | TACR1 (0.54) | CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134124-A | USE OF A STATIN DERIVATIVE IN THE TREATMENT OF EYE COMPLAINTS | SANOFI (FR) | 1992-07-28 | — | — | US | disclosed |