Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | GPR132 | Q9UNW8 | 4/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.39 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.38 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.38 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724951 | 0.88 | KMT2A (0.46) | CYP1A2CTSLCTSBGPR132HDAC8 | |
| SCHEMBL7295646 | 0.84 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C9CYP2C19HDAC8 | |
| SCHEMBL7295654 | 0.84 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C9CYP2C19HDAC8 | |
| SCHEMBL7286963 | 0.82 | PSMB5 (0.51) | MMP12CTSLCTSBMMP9MMP8 | |
| SCHEMBL7286971 | 0.82 | PSMB5 (0.51) | MMP12CTSLCTSBMMP9MMP8 | |
| SCHEMBL7285504 | 0.82 | CTSS (0.50) | CTSLCTSBHDAC8PSMB11PSMA7 | |
| SCHEMBL7285491 | 0.82 | CTSS (0.50) | CTSLCTSBHDAC8PSMB11PSMA7 | |
| SCHEMBL7442083 | 0.80 | REN (0.40) | POLBCTSLCTSBMMP9MMP8 | |
| SCHEMBL7286309 | 0.79 | TACR1 (0.54) | CTSLCTSB | |
| SCHEMBL7286303 | 0.79 | TACR1 (0.54) | CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134124-A | USE OF A STATIN DERIVATIVE IN THE TREATMENT OF EYE COMPLAINTS | SANOFI (FR) | 1992-07-28 | — | — | US | disclosed |