SCHEMBL9725288

SCHEMBL9725288

O=c1oc2cc(S)ccc2c2c1CCCC2

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.67
ALDH1A1 P00352 3/20 0.67
HPGD P15428 3/20 0.67
TSHR P16473 3/20 0.67
HSD17B10 Q99714 3/20 0.67
GLA P06280 1/20 0.67
GAA P10253 1/20 0.67
CASP1 P29466 1/20 0.67
CASP7 P55210 1/20 0.67
CYP1A2 P05177 1/20 0.65
MAOA P21397 1/20 0.62
STS P08842 14/20 0.56
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CYP19A1 P11511 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21587877 0.85 KDM4E (0.69) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL30465069 0.80 KDM4E (1.00) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL3768560 0.80 KDM4E (1.00) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL4710494 0.80 ALDH1A1 (0.67) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL7532636 0.80 ALDH1A1 (0.67) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL3762769 0.79 CYP1A2 (1.00) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL3625077 0.79 CYP1A2 (1.00) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL31331899 0.77 MAOA (0.67) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL3757463 0.77 MAOA (1.00) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL7562741 0.75 KDM4E (0.60) KDM4EALDH1A1HPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5169838-A Anticoagulants FOURNIER INDUSTRIE ET SANTE (FR) 1992-12-08 US disclosed