Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725384 | 0.89 | ALDH1A1 (0.56) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4233854 | 0.85 | HCAR3 (0.60) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL2472513 | 0.83 | KAT2B (0.60) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL10804569 | 0.83 | MEN1 (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL21815032 | 0.83 | MAPT (0.64) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL1009970 | 0.83 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6938256 | 0.82 | MEN1 (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL10781769 | 0.82 | KAT2B (0.61) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL9725410 | 0.82 | ALDH1A1 (0.72) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1594797 | 0.82 | ALDH1A1 (0.72) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |