Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723280 | 0.78 | ACHE (0.41) | MAPTALDH1A1LMNACA1CA2 | |
| SCHEMBL7723242 | 0.78 | CA1 (0.48) | MAPTALDH1A1MAPK1HPGDCA1 | |
| SCHEMBL17024102 | 0.78 | MAPT (0.48) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8400417 | 0.76 | ALDH1A1 (0.40) | MAPTALDH1A1NPC1LMNAMEN1 | |
| SCHEMBL1262500 | 0.75 | LMNA (0.47) | ALDH1A1LMNATSHR | |
| SCHEMBL2546366 | 0.74 | NR1H4 (0.46) | MAPTALDH1A1MAPK1NPC1HPGD | |
| SCHEMBL17024114 | 0.73 | LMNA (0.46) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8140565 | 0.73 | MAPT (0.48) | MAPTALDH1A1MAPK1NPC1HPGD | |
| SCHEMBL7795835 | 0.72 | MAPT (0.44) | MAPTALDH1A1MAPK1NPC1HPGD | |
| SCHEMBL3786415 | 0.71 | MAPT (0.47) | MAPTALDH1A1MAPK1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151195-A | Copolymer of acrylamide containing quarternary ammonium group | PETROLITE CORPORATION (US) | 1992-09-29 | — | — | US | disclosed |
| EP-0248519-A2 | Flotation-aid composition and method of use thereof | PETROLITE CORPORATION (US) | 1987-12-09 | — | — | EP | disclosed |