Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | AOC2 | O75106 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723242 | 0.81 | CA1 (0.48) | ALDH1A1KDM4ECYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7723280 | 0.81 | ACHE (0.41) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL1262500 | 0.78 | LMNA (0.47) | ALDH1A1MAOALMNATSHRKDM4E | |
| SCHEMBL9725561 | 0.76 | MAPT (0.41) | ALDH1A1MAOBLMNAMEN1KMT2A | |
| SCHEMBL23912995 | 0.71 | ALDH1A1 (0.52) | ALDH1A1NFE2L2MAOAMAOBLMNA | |
| SCHEMBL1259185 | 0.70 | NFE2L2 (0.46) | ALDH1A1NFE2L2MAOAMAOBLMNA | |
| SCHEMBL7157810 | 0.70 | KMT2A (0.34) | ALDH1A1NFE2L2HTTMAOAMAOB | |
| SCHEMBL30046823 | 0.67 | NFE2L2 (0.43) | ALDH1A1NFE2L2MAOAMAOBLMNA | |
| SCHEMBL6035001 | 0.67 | ACHE (0.48) | ALDH1A1LMNAMEN1KMT2AGAA | |
| SCHEMBL1835550 | 0.67 | LMNA (0.64) | LMNAMEN1KMT2ATSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918759-A1 | NOVEL THIAZOLIDONE-2 DERIVATIVES, 4-DIKETONE SUBSTITUTED, METHOD FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | MERCK PATENT GmbH (DE) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997047612-A1 | NOVEL THIAZOLIDONE-2 DERIVATIVES, 4-DIKETONE SUBSTITUTED, METHOD FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | MERCK PATENT GMBH (DE) | 1997-12-18 | — | — | WO | disclosed |