Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.43 |
| ▸ | MMP2 | P08253 | 7/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 5/20 | 0.42 |
| ▸ | MMP8 | P22894 | 5/20 | 0.42 |
| ▸ | NMBR | P28336 | 3/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725888 | 0.81 | REN (0.47) | REN | |
| SCHEMBL9725823 | 0.81 | REN (0.47) | REN | |
| SCHEMBL9725820 | 0.71 | REN (0.49) | REN | |
| SCHEMBL9849679 | 0.69 | METAP2 (0.42) | REN | |
| SCHEMBL9849682 | 0.69 | METAP2 (0.42) | REN | |
| SCHEMBL9741102 | 0.69 | MMP2 (0.57) | RENMMP2MMP1MMP9MMP8 | |
| SCHEMBL7278377 | 0.68 | PSEN1 (0.46) | REN | |
| SCHEMBL7278381 | 0.68 | PSEN1 (0.46) | REN | |
| SCHEMBL7288300 | 0.68 | REN (0.47) | REN | |
| SCHEMBL7288303 | 0.68 | REN (0.47) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106835-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | claimed |