Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 9/20 | 0.57 |
| ▸ | MMP9 | P14780 | 7/20 | 0.57 |
| ▸ | MMP8 | P22894 | 7/20 | 0.57 |
| ▸ | REN | P00797 | 8/20 | 0.55 |
| ▸ | MMP1 | P03956 | 4/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | IL1RN | P18510 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740864 | 0.77 | MMP2 (0.55) | MMP2MMP9MMP8RENMMP1 | |
| SCHEMBL9740857 | 0.77 | MMP2 (0.55) | MMP2MMP9MMP8RENMMP1 | |
| SCHEMBL9740882 | 0.74 | MMP2 (0.54) | MMP2MMP9MMP8RENIL1RN | |
| SCHEMBL9740887 | 0.74 | MMP2 (0.54) | MMP2MMP9MMP8RENIL1RN | |
| SCHEMBL9739657 | 0.72 | REN (0.51) | REN | |
| SCHEMBL9739660 | 0.72 | REN (0.51) | REN | |
| SCHEMBL9740075 | 0.72 | REN (0.48) | REN | |
| SCHEMBL9740080 | 0.72 | REN (0.48) | REN | |
| SCHEMBL7369317 | 0.71 | REN (0.52) | REN | |
| SCHEMBL9740310 | 0.71 | REN (0.41) | MMP2MMP9MMP8RENMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104869-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-04-14 | — | — | US | claimed |