Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 9/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727095 | 0.89 | DRD4 (0.72) | DRD4MCHR1SIGMAR1 | |
| SCHEMBL9727072 | 0.81 | UTS2R (0.68) | DRD4MCHR1DRD2DRD3 | |
| Iodide SCHEMBL9852255 | 0.80 | DRD4 (0.60) | DRD4MCHR1SIGMAR1 | |
| SCHEMBL9852082 | 0.80 | DRD4 (0.73) | DRD4MCHR1SIGMAR1 | |
| SCHEMBL9727149 | 0.79 | DRD4 (0.58) | DRD4MCHR1SIGMAR1 | |
| SCHEMBL9727135 | 0.78 | DRD4 (0.67) | DRD4MCHR1SIGMAR1 | |
| SCHEMBL9727235 | 0.78 | DRD4 (0.58) | DRD4MCHR1SIGMAR1 | |
| Dimethylamine SCHEMBL9852061 | 0.77 | DRD4 (0.63) | DRD4MCHR1SIGMAR1 | |
| SCHEMBL9727173 | 0.77 | SIGMAR1 (0.57) | DRD4MCHR1SIGMAR1 | |
| SCHEMBL9727123 | 0.77 | DRD4 (0.69) | DRD4MCHR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098915-A | Antiarrhythmia agents | G. D. SEARLE & CO. (US) | 1992-03-24 | — | — | US | claimed |