Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.56 |
| ▸ | DRD4 | P21917 | 3/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727091 | 0.89 | DRD4 (0.70) | UTS2RRAB9AMCHR1DRD4DRD2 | |
| SCHEMBL9727078 | 0.81 | DRD4 (0.57) | MCHR1DRD4DRD2DRD3 | |
| Iodide SCHEMBL9852252 | 0.80 | DRD4 (0.59) | UTS2RMCHR1DRD4DRD2ACHE | |
| SCHEMBL9852062 | 0.79 | DRD4 (0.71) | UTS2RMCHR1DRD4DRD2ACHE | |
| SCHEMBL9852064 | 0.79 | MCHR1 (0.66) | UTS2RMCHR1DRD4ACHE | |
| SCHEMBL9727136 | 0.78 | DRD4 (0.67) | RAB9ADRD4ACHE | |
| SCHEMBL9727140 | 0.78 | UTS2R (0.73) | UTS2RRAB9AMCHR1DRD4ACHE | |
| SCHEMBL9727231 | 0.77 | MCHR1 (0.64) | MCHR1DRD4ACHE | |
| SCHEMBL9852060 | 0.77 | ACHE (0.60) | UTS2RRAB9AMCHR1DRD4ACHE | |
| SCHEMBL9727131 | 0.77 | MAOB (0.74) | UTS2RRAB9AMCHR1DRD4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098915-A | Antiarrhythmia agents | G. D. SEARLE & CO. (US) | 1992-03-24 | — | — | US | claimed |