Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.73 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | CCR3 | P51677 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727095 | 0.91 | DRD4 (0.72) | DRD4MCHR1SIGMAR1MAOBCCR3 | |
| SCHEMBL9727135 | 0.86 | DRD4 (0.67) | DRD4MCHR1SIGMAR1MAOB | |
| SCHEMBL9852245 | 0.85 | DRD4 (0.55) | DRD4MCHR1SIGMAR1MAOBACHE | |
| Dimethylamine SCHEMBL9852061 | 0.85 | DRD4 (0.63) | DRD4MCHR1SIGMAR1MAOB | |
| SCHEMBL9727235 | 0.83 | DRD4 (0.58) | DRD4MCHR1SIGMAR1MAOBKCNH2 | |
| Iodide SCHEMBL9852255 | 0.82 | DRD4 (0.60) | DRD4MCHR1SIGMAR1MAOBKCNH2 | |
| SCHEMBL9727123 | 0.81 | DRD4 (0.69) | DRD4MCHR1SIGMAR1MAOB | |
| SCHEMBL9727173 | 0.81 | SIGMAR1 (0.57) | DRD4MCHR1SIGMAR1MAOBACHE | |
| SCHEMBL9852062 | 0.81 | DRD4 (0.71) | DRD4MCHR1SIGMAR1MAOBKCNH2 | |
| SCHEMBL9727149 | 0.81 | DRD4 (0.58) | DRD4MCHR1SIGMAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |