Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 9/20 | 0.69 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.53 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727135 | 0.92 | DRD4 (0.67) | DRD4MCHR1SIGMAR1MAOBSLC6A12 | |
| SCHEMBL9727173 | 0.92 | SIGMAR1 (0.57) | DRD4MCHR1SIGMAR1MAOBSLC6A12 | |
| Dimethylamine SCHEMBL9852061 | 0.89 | DRD4 (0.63) | DRD4MCHR1SIGMAR1MAOBSLC6A12 | |
| SCHEMBL9727095 | 0.89 | DRD4 (0.72) | DRD4MCHR1SIGMAR1MAOBSMN1; SMN2 | |
| SCHEMBL9727255 | 0.87 | DRD4 (0.66) | DRD4SIGMAR1MAOB | |
| SCHEMBL9852073 | 0.87 | DRD4 (0.54) | DRD4MCHR1SIGMAR1MAOB | |
| SCHEMBL9483648 | 0.85 | DRD4 (0.52) | DRD4MCHR1MAOBSLC6A12SLC6A13 | |
| SCHEMBL9727149 | 0.85 | DRD4 (0.58) | DRD4MCHR1SIGMAR1MAOBSMN1; SMN2 | |
| SCHEMBL9727235 | 0.83 | DRD4 (0.58) | DRD4MCHR1SIGMAR1MAOB | |
| SCHEMBL9852082 | 0.81 | DRD4 (0.73) | DRD4MCHR1SIGMAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098915-A | Antiarrhythmia agents | G. D. SEARLE & CO. (US) | 1992-03-24 | — | — | US | claimed |