Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.61 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | BACE1 | P56817 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727135 | 0.88 | DRD4 (0.67) | DRD4SIGMAR1MAOBTMEM97 | |
| SCHEMBL9727123 | 0.87 | DRD4 (0.69) | DRD4SIGMAR1MAOB | |
| SCHEMBL9727173 | 0.87 | SIGMAR1 (0.57) | DRD4SIGMAR1ACHEMAOB | |
| SCHEMBL9852241 | 0.86 | DRD4 (0.60) | DRD4SIGMAR1BCHEACHEBACE1 | |
| Dimethylamine SCHEMBL9852061 | 0.85 | DRD4 (0.63) | DRD4SIGMAR1MAOB | |
| SCHEMBL9727177 | 0.85 | DRD4 (0.54) | DRD4SIGMAR1ACHEMAOB | |
| SCHEMBL9727095 | 0.84 | DRD4 (0.72) | DRD4SIGMAR1ACHEMAOB | |
| SCHEMBL9852237 | 0.84 | DRD4 (0.57) | DRD4SIGMAR1ACHEMAOB | |
| SCHEMBL9852073 | 0.83 | DRD4 (0.54) | DRD4SIGMAR1MAOB | |
| SCHEMBL9483648 | 0.81 | DRD4 (0.52) | DRD4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098915-A | Antiarrhythmia agents | G. D. SEARLE & CO. (US) | 1992-03-24 | — | — | US | claimed |
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |