Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 3/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.65 |
| ▸ | DRD3 | P35462 | 1/20 | 0.65 |
| ▸ | DRD4 | P21917 | 2/20 | 0.65 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.65 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.65 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727117 | 0.92 | DRD4 (0.67) | MAOBRAB9AACHEKCNH2MCHR1 | |
| SCHEMBL9727166 | 0.92 | ACHE (0.66) | MAOBRAB9AACHEKCNH2MCHR1 | |
| SCHEMBL16927793 | 0.91 | MAOB (0.63) | MAOBRAB9AACHEKCNH2MCHR1 | |
| SCHEMBL14096071 | 0.90 | NPC1 (0.64) | MAOBRAB9AACHEKCNH2MCHR1 | |
| SCHEMBL650728 | 0.89 | ACHE (0.76) | MAOBACHEKCNH2MCHR1DRD4 | |
| SCHEMBL9852059 | 0.88 | UTS2R (0.64) | MAOBRAB9AACHEKCNH2MCHR1 | |
| SCHEMBL9727091 | 0.88 | DRD4 (0.70) | MAOBRAB9AACHEKCNH2MCHR1 | |
| SCHEMBL9727243 | 0.88 | DRD4 (0.69) | MAOBRAB9AACHEKCNH2MCHR1 | |
| SCHEMBL9852055 | 0.88 | MCHR1 (0.66) | MAOBRAB9AACHEKCNH2MCHR1 | |
| SCHEMBL9852062 | 0.87 | DRD4 (0.71) | MAOBACHEKCNH2MCHR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098915-A | Antiarrhythmia agents | G. D. SEARLE & CO. (US) | 1992-03-24 | — | — | US | claimed |
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |