Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.71 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | ACHE | P22303 | 2/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.58 |
| ▸ | CCR3 | P51677 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727091 | 0.90 | DRD4 (0.70) | DRD4MCHR1KCNH2ACHESIGMAR1 | |
| SCHEMBL9727131 | 0.87 | MAOB (0.74) | DRD4MCHR1KCNH2ACHEMAOB | |
| SCHEMBL9852060 | 0.86 | ACHE (0.60) | DRD4MCHR1KCNH2ACHESIGMAR1 | |
| SCHEMBL6333249 | 0.84 | MCHR1 (0.87) | DRD4MCHR1KCNH2ACHEMAOB | |
| SCHEMBL16356197 | 0.82 | DRD4 (0.60) | DRD4MCHR1KCNH2ACHESIGMAR1 | |
| SCHEMBL9727166 | 0.82 | ACHE (0.66) | DRD4MCHR1KCNH2ACHESIGMAR1 | |
| SCHEMBL9727117 | 0.82 | DRD4 (0.67) | DRD4MCHR1KCNH2ACHESIGMAR1 | |
| Iodide SCHEMBL9852252 | 0.82 | DRD4 (0.59) | DRD4MCHR1KCNH2ACHESIGMAR1 | |
| SCHEMBL9852082 | 0.81 | DRD4 (0.73) | DRD4MCHR1KCNH2ACHESIGMAR1 | |
| SCHEMBL9727140 | 0.81 | UTS2R (0.73) | DRD4MCHR1KCNH2ACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |