Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.59 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727131 | 0.88 | MAOB (0.74) | MCHR1KCNH2RAB9AMAOBUTS2R | |
| SCHEMBL9727166 | 0.87 | ACHE (0.66) | MCHR1KCNH2NPC1RAB9ATP53 | |
| SCHEMBL9727117 | 0.87 | DRD4 (0.67) | MCHR1KCNH2NPC1RAB9ATP53 | |
| SCHEMBL9482251 | 0.87 | MAOB (0.57) | MCHR1KCNH2NPC1RAB9ATP53 | |
| SCHEMBL9727091 | 0.85 | DRD4 (0.70) | MCHR1KCNH2RAB9AMAOBUTS2R | |
| SCHEMBL9852059 | 0.85 | UTS2R (0.64) | MCHR1KCNH2NPC1RAB9ATP53 | |
| SCHEMBL16927793 | 0.84 | MAOB (0.63) | MCHR1KCNH2NPC1RAB9ATP53 | |
| SCHEMBL9727243 | 0.82 | DRD4 (0.69) | MCHR1KCNH2NPC1RAB9ATP53 | |
| SCHEMBL9727140 | 0.82 | UTS2R (0.73) | MCHR1KCNH2RAB9AMAOBUTS2R | |
| SCHEMBL9852062 | 0.80 | DRD4 (0.71) | MCHR1KCNH2MAOBUTS2RACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |