Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727091 | 0.89 | DRD4 (0.70) | DRD4MAOBACHEKDM4EALDH1A1 | |
| Iodide SCHEMBL9852252 | 0.80 | DRD4 (0.59) | DRD4MAOBACHEKDM4EALDH1A1 | |
| SCHEMBL9727116 | 0.80 | MAOB (0.73) | DRD4MAOBACHE | |
| SCHEMBL9727049 | 0.80 | MAOB (0.80) | DRD4MAOBACHE | |
| SCHEMBL9852062 | 0.79 | DRD4 (0.71) | DRD4MAOBACHEKDM4EALDH1A1 | |
| SCHEMBL9727095 | 0.79 | DRD4 (0.72) | DRD4MAOBACHEALDH1A1 | |
| SCHEMBL9852064 | 0.79 | MCHR1 (0.66) | DRD4ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL9727140 | 0.78 | UTS2R (0.73) | DRD4MAOBACHEKDM4EALDH1A1 | |
| SCHEMBL9727072 | 0.78 | UTS2R (0.68) | DRD4ACHERAB9A | |
| SCHEMBL9872559 | 0.78 | DRD4 (0.78) | DRD4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098915-A | Antiarrhythmia agents | G. D. SEARLE & CO. (US) | 1992-03-24 | — | — | US | claimed |
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |