Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.73 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727091 | 0.89 | DRD4 (0.70) | UTS2RHTR1AHTR2BACHEMAOB | |
| SCHEMBL9727131 | 0.85 | MAOB (0.74) | UTS2RACHEMAOBDRD4RAB9A | |
| SCHEMBL9727117 | 0.84 | DRD4 (0.67) | UTS2RACHEMAOBDRD4LMNA | |
| SCHEMBL9727166 | 0.84 | ACHE (0.66) | UTS2RACHEMAOBDRD4RAB9A | |
| SCHEMBL7132070 | 0.83 | LTA4H (0.69) | UTS2RRAB9AHPGD | |
| SCHEMBL9852059 | 0.83 | UTS2R (0.64) | UTS2RACHEMAOBDRD4RAB9A | |
| SCHEMBL9871439 | 0.82 | UTS2R (0.69) | UTS2RDRD4MCHR1 | |
| SCHEMBL9852055 | 0.82 | MCHR1 (0.66) | UTS2RACHEMAOBDRD4RAB9A | |
| SCHEMBL16927793 | 0.81 | MAOB (0.63) | UTS2RACHEMAOBDRD4ALDH1A1 | |
| SCHEMBL9852062 | 0.81 | DRD4 (0.71) | UTS2RHTR1AHTR2BACHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098915-A | Antiarrhythmia agents | G. D. SEARLE & CO. (US) | 1992-03-24 | — | — | US | claimed |
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |