Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6084174 | 0.84 | RAB9A (0.78) | RAB9APOLBNPC1ALDH1A1HPGD | |
| SCHEMBL6084166 | 0.84 | RAB9A (0.78) | RAB9APOLBNPC1ALDH1A1HPGD | |
| SCHEMBL9727131 | 0.83 | MAOB (0.74) | RAB9AUTS2RMAOB | |
| Hydrochloric Acid SCHEMBL9343546 | 0.81 | RAB9A (0.76) | RAB9APOLBNPC1ALDH1A1HPGD | |
| SCHEMBL9727166 | 0.80 | ACHE (0.66) | RAB9ANPC1SMN1; SMN2TP53UTS2R | |
| SCHEMBL9727126 | 0.80 | RAB9A (0.70) | RAB9APOLBNPC1ALDH1A1HPGD | |
| SCHEMBL9727117 | 0.80 | DRD4 (0.67) | RAB9ANPC1NPSR1SMN1; SMN2TP53 | |
| SCHEMBL16927793 | 0.79 | MAOB (0.63) | RAB9ANPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9852059 | 0.79 | UTS2R (0.64) | RAB9ANPC1SMN1; SMN2TP53UTS2R | |
| SCHEMBL9727091 | 0.79 | DRD4 (0.70) | RAB9AALDH1A1HPGDKDM4EUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098915-A | Antiarrhythmia agents | G. D. SEARLE & CO. (US) | 1992-03-24 | — | — | US | claimed |
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |