Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CCR1 | P32246 | 5/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727131 | 0.83 | MAOB (0.74) | RAB9AMAOBUTS2R | |
| SCHEMBL9727166 | 0.80 | ACHE (0.66) | RAB9AMAOBNPC1SMN1; SMN2UTS2R | |
| SCHEMBL9727117 | 0.80 | DRD4 (0.67) | RAB9AMAOBNPC1SMN1; SMN2UTS2R | |
| SCHEMBL9727199 | 0.80 | RAB9A (0.74) | RAB9APOLBMAOBSLC6A2SLC6A4 | |
| SCHEMBL16927793 | 0.80 | MAOB (0.63) | RAB9AMAOBNPC1KDM4EALDH1A1 | |
| SCHEMBL9727243 | 0.79 | DRD4 (0.69) | RAB9AMAOBNPC1SMN1; SMN2UTS2R | |
| SCHEMBL9852059 | 0.77 | UTS2R (0.64) | RAB9AMAOBNPC1SMN1; SMN2UTS2R | |
| SCHEMBL9727091 | 0.77 | DRD4 (0.70) | RAB9AMAOBKDM4EALDH1A1HPGD | |
| SCHEMBL9852055 | 0.76 | MCHR1 (0.66) | RAB9AMAOBNPC1SMN1; SMN2UTS2R | |
| SCHEMBL9852142 | 0.76 | CCR1 (0.54) | RAB9ACCR1MAOBNPC1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098915-A | Antiarrhythmia agents | G. D. SEARLE & CO. (US) | 1992-03-24 | — | — | US | claimed |
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |