Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727395 | 0.84 | KMT2A (0.42) | HTR6MEN1KMT2AGAALMNA | |
| SCHEMBL9727446 | 0.83 | MEN1 (0.41) | HTR6MEN1KMT2AGAALMNA | |
| SCHEMBL9732296 | 0.73 | HTR6 (0.42) | HTR6 | |
| SCHEMBL20380052 | 0.73 | HTR6 (0.41) | HTR6 | |
| SCHEMBL9727352 | 0.72 | HTR6 (0.55) | HTR6 | |
| SCHEMBL1013307 | 0.71 | HTR6 (0.58) | HTR6 | |
| SCHEMBL6797106 | 0.70 | HTR6 (0.40) | HTR6 | |
| SCHEMBL9727309 | 0.69 | HTR6 (0.49) | HTR6MEN1KMT2AGAADRD3 | |
| SCHEMBL7380549 | 0.66 | PKM (0.62) | HTR6MEN1KMT2AGAALMNA | |
| SCHEMBL7674989 | 0.66 | MGLL (0.47) | HTR6LMNATSHRSTAT3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164514-A | Antispasmodics | ROUSSEL UCLAF (FR) | 1992-11-17 | — | — | US | disclosed |
| US-5081130-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1992-01-14 | — | — | US | disclosed |
| US-4990531-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1991-02-05 | — | — | US | disclosed |
| EP-0335758-A2 | Derivatives of 1-arylsulfonyl-2-pyrolidinone, process for their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1989-10-04 | — | — | EP | disclosed |