Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D known ✓ | O15399 | 2/20 | 0.50 |
| ▸ | GRIN2A known ✓ | Q12879 | 2/20 | 0.50 |
| ▸ | GRIN2B known ✓ | Q13224 | 2/20 | 0.50 |
| ▸ | GRIN2C known ✓ | Q14957 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PKLR | P30613 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569691 | 0.83 | GRIN2D (0.69) | GRIN2DGRIN2AGRIN2BGRIN2CPOLB | |
| SCHEMBL30943793 | 0.83 | GRIN2D (0.69) | GRIN2DGRIN2AGRIN2BGRIN2CPOLB | |
| SCHEMBL9728234 | 0.81 | GRIN2D (0.68) | GRIN2DGRIN2AGRIN2BGRIN2CPOLB | |
| SCHEMBL9244803 | 0.79 | GRIN2A (0.49) | GRIN2DGRIN2AGRIN2BGRIN2CPOLB | |
| Lithium Ion SCHEMBL9245069 | 0.79 | GRIN2A (0.49) | GRIN2DGRIN2AGRIN2BGRIN2CGPR35 | |
| Pamoic Acid SCHEMBL587128 | 0.79 | GPR35 (0.71) | POLBGPR35MEN1KMT2ACYP2D6 | |
| SCHEMBL28513748 | 0.78 | MEN1 (0.62) | GRIN2DGRIN2AGRIN2BGRIN2CPOLB | |
| Pamoic Acid SCHEMBL248780 | 0.75 | GPR35 (0.71) | POLBGPR35MEN1KMT2ACYP2D6 | |
| Pamoic Acid SCHEMBL11315960 | 0.75 | GPR35 (0.71) | POLBGPR35MEN1KMT2ACYP2D6 | |
| Pamoic Acid SCHEMBL1457853 | 0.75 | GPR35 (0.71) | POLBGPR35MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273605-B1 | ULTRA-FINE PARTICULATED POLYMER LATEX AND COMPOSITION CONTAINING THE SAME | LION CORPORATION (JP) | 1992-02-19 | — | — | EP | disclosed |
| US-4943612-A | ANIONIC, CATIONIC, AND NONIONIC EMULSIFIERS | LION CORPORATION (JP) | 1990-07-24 | — | — | US | disclosed |
| EP-0273605-A2 | Ultra-fine particulated polymer latex and composition containing the same | LION CORPORATION (JP) | 1988-07-06 | — | — | EP | disclosed |