Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728467 | 0.84 | RAB9A (0.72) | KDM4EMAPTALDH1A1KMT2ANPC1 | |
| SCHEMBL9728645 | 0.82 | RAB9A (0.61) | KDM4EMAPTALDH1A1KMT2ANPC1 | |
| SCHEMBL9728332 | 0.81 | MAPT (0.52) | KDM4EMAPTALDH1A1KMT2ANPC1 | |
| SCHEMBL5178791 | 0.73 | ALDH1A1 (0.54) | KDM4EMAPTALDH1A1KMT2ANPC1 | |
| SCHEMBL10004321 | 0.72 | KDM4E (0.58) | KDM4EMAPTALDH1A1KMT2ANPC1 | |
| SCHEMBL12567028 | 0.72 | GAA (0.50) | MAPTALDH1A1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL32666080 | 0.72 | KDM4E (0.69) | KDM4EMAPTALDH1A1KMT2ANPC1 | |
| SCHEMBL1101889 | 0.69 | KDM4E (0.66) | KDM4EMAPTALDH1A1KMT2ANPC1 | |
| SCHEMBL9823743 | 0.69 | KDM4E (0.64) | KDM4EMAPTALDH1A1KMT2ANPC1 | |
| SCHEMBL9728402 | 0.68 | RAB9A (0.57) | KDM4EMAPTALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | claimed |
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |