Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728470 | 0.82 | RAB9A (0.68) | MAPTHSD17B10PDE11APDE10AKMT2A | |
| SCHEMBL9728272 | 0.82 | RAB9A (0.56) | MAPTHSD17B10PDE11APDE10AHPGD | |
| SCHEMBL9728472 | 0.81 | KDM4E (0.57) | MAPTHSD17B10PDE11APDE10AHPGD | |
| SCHEMBL9728142 | 0.79 | MEN1 (0.56) | MAPTHSD17B10KMT2AKDM4ENPC1 | |
| SCHEMBL9729063 | 0.76 | MAPK1 (0.57) | MAPTHSD17B10HPGDKMT2AKDM4E | |
| SCHEMBL9729002 | 0.71 | ALPL (0.51) | HPGDHTTKMT2AGAAKDM4E | |
| SCHEMBL13977074 | 0.70 | KDM4E (0.57) | MAPTHSD17B10HPGDHTTGAA | |
| SCHEMBL7223862 | 0.69 | KDM4E (0.46) | MAPTHSD17B10HPGDKMT2AGAA | |
| SCHEMBL7224007 | 0.68 | EGFR (0.50) | MAPTHSD17B10HPGDKMT2AGAA | |
| SCHEMBL3679747 | 0.67 | NPC1 (0.68) | MAPTHSD17B10HPGDHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | claimed |
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |