Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728508 | 0.91 | KMT2A (0.47) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL9818479 | 0.87 | POLB (0.52) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL9728781 | 0.87 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL19152011 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL9728491 | 0.85 | NPC1 (0.53) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL9409114 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL10400661 | 0.75 | PKM (0.66) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL14698797 | 0.73 | ALDH1A1 (0.48) | ALDH1A1KMT2AHPGDSMN1; SMN2GAA | |
| SCHEMBL11411919 | 0.72 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL3413960 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KMT2AHPGDSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | disclosed |