Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728484 | 0.91 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL9728781 | 0.86 | ALDH1A1 (0.54) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL9818479 | 0.86 | POLB (0.52) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL9728491 | 0.84 | NPC1 (0.53) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL19152011 | 0.76 | ALDH1A1 (0.56) | KMT2AMEN1RAB9AALDH1A1KDM4E | |
| SCHEMBL9728569 | 0.74 | ALDH1A1 (0.74) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL9728502 | 0.71 | KMT2A (0.64) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL7374257 | 0.71 | CHRNB2 (0.47) | KMT2ANPC1RAB9APOLBALDH1A1 | |
| SCHEMBL9081849 | 0.70 | ALDH1A1 (0.66) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL14698797 | 0.70 | ALDH1A1 (0.48) | KMT2ANPC1RAB9APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | claimed |
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | disclosed |