Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728484 | 0.87 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AALOX12HTT | |
| SCHEMBL9728508 | 0.86 | KMT2A (0.47) | ALDH1A1MEN1KMT2AALOX12NPSR1 | |
| SCHEMBL19152011 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AALOX12NPSR1 | |
| SCHEMBL9728491 | 0.79 | NPC1 (0.53) | ALDH1A1MEN1KMT2AALOX12HTT | |
| SCHEMBL9818479 | 0.79 | POLB (0.52) | ALDH1A1MEN1KMT2AALOX12NPSR1 | |
| SCHEMBL9728350 | 0.76 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AALOX12NPSR1 | |
| SCHEMBL9728776 | 0.73 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AALOX12NPSR1 | |
| SCHEMBL12858639 | 0.73 | CRHBP (0.66) | ALDH1A1KMT2AALOX12NPSR1HTT | |
| SCHEMBL26637634 | 0.70 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AALOX12NPSR1 | |
| SCHEMBL2153243 | 0.70 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AALOX12NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | claimed |
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | disclosed |