Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 9/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728493 | 0.83 | CACNA1F (0.41) | MEN1ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL9728401 | 0.73 | CACNA1F (0.51) | MEN1KMT2APOLB | |
| SCHEMBL9728418 | 0.71 | ADRB2 (0.53) | ALDH1A1KMT2ABTKALOX15KDM4E | |
| SCHEMBL19729369 | 0.69 | GPR119 (0.41) | PIK3CDGPR119NPBWR1MCHR1ALOX15 | |
| SCHEMBL21341518 | 0.67 | GPR119 (0.39) | MEN1ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL19729370 | 0.67 | PIK3CD (0.45) | PIK3CDGPR119NPBWR1MCHR1KDM4E | |
| SCHEMBL1430070 | 0.67 | GABRA1 (0.43) | MEN1ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL9728544 | 0.67 | ADRB2 (0.44) | ALDH1A1LMNAKMT2APIK3CDGPR119 | |
| SCHEMBL19729367 | 0.67 | PIK3CD (0.43) | MEN1KMT2ASMN1; SMN2NPSR1PIK3CD | |
| SCHEMBL27282789 | 0.66 | CLEC4M (0.56) | MEN1ALDH1A1KMT2ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153203-A | QUINOLONE DERIVATIVES AND SALTS THEREOF, PREPARATION PROCESSES THEREOF, AND ANTIBACTERIAL AGENTS CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0390215-A2 | Quinolone derivatives and salts thereof, preparation process es thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1990-10-03 | — | — | EP | disclosed |