Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.58 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL971323 | 0.90 | ALDH1A1 (0.72) | MAPTALDH1A1TDP1THRBCYP3A4 | |
| SCHEMBL11851928 | 0.88 | MAPT (0.76) | MAPTALDH1A1TDP1THRBCYP3A4 | |
| SCHEMBL11863153 | 0.84 | MAPT (0.68) | MAPTALDH1A1TDP1THRBCYP3A4 | |
| SCHEMBL11855172 | 0.84 | MAPT (0.82) | MAPTALDH1A1TDP1THRBCYP3A4 | |
| SCHEMBL11860789 | 0.84 | MAPT (0.82) | MAPTALDH1A1TDP1THRBCYP3A4 | |
| SCHEMBL11858844 | 0.81 | ALDH1A1 (0.62) | MAPTALDH1A1TDP1THRBCYP3A4 | |
| SCHEMBL11861509 | 0.81 | ALDH1A1 (0.62) | MAPTALDH1A1TDP1THRBCYP3A4 | |
| SCHEMBL7329653 | 0.81 | TDP1 (0.66) | MAPTALDH1A1TDP1THRBCYP3A4 | |
| SCHEMBL25247272 | 0.80 | MGLL (0.75) | MAPTALDH1A1TDP1THRBMGLL | |
| SCHEMBL25245987 | 0.80 | MGLL (0.75) | MAPTALDH1A1TDP1THRBMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102231996-B | Skin treatment agent comprising carboxylic acid-substituted idebenone derivative, and preparation method and use thereof | ARDEN ELIZABETH INC | 2014-11-26 | — | — | CN | disclosed |
| EP-2183257-B1 | ESTERS OF LONG-CHAIN ALCOHOLS AND PREPARATION THEROF | EASTMAN CHEM CO (US) | 2013-03-20 | — | — | EP | disclosed |
| CN-101938976-B | Esters of long-chain alcohols and preparation thereof | EASTMAN CHEM CO | 2012-12-12 | — | — | CN | disclosed |
| CN-102231996-A | Skin treatment agent comprising carboxylic acid-substituted idebenone derivative, and preparation method and use thereof | PHARMA COSMETIX RES LLC | 2011-11-02 | — | — | CN | disclosed |
| US-7927855-B2 | Esters of long-chain alcohols and preparation thereof | EASTMAN CHEMICAL COMPANY (US) | 2011-04-19 | — | — | US | disclosed |
| US-7872047-B2 | Esters of long-chain alcohols and preparation thereof | EASTMAN CHEMICAL COMPANY (US) | 2011-01-18 | — | — | US | disclosed |
| CN-101938976-A | Esters of long-chain alcohols and preparation thereof | EASTMAN CHEM CO | 2011-01-05 | — | — | CN | disclosed |
| EP-2249777-A1 | ESTERS OF LONG-CHAIN ALCOHOLS AND THEIR USE TO TREAT THE SKIN | Eastman Chemical Company (US) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009099524-A1 | ESTERS OF LONG-CHAIN ALCOHOLS AND THEIR USE TO TREAT THE SKIN | EASTMAN CHEMICAL COMPANY (US) | 2009-08-13 | — | — | WO | disclosed |
| US-20090203779-A1 | ESTERS OF LONG-CHAIN ALCOHOLS AND PREPARATION THEREOF | EASTMAN CHEMICAL COMPANY (US) | 2009-08-13 | — | — | US | disclosed |
| US-20090042271-A1 | Esters of long-chain alcohols and preparation thereof | EASTMAN CHEMICAL COMPANY | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042271-A1 | Esters of long-chain alcohols and preparation thereof | ADH1A, ADH1C, ADH5 | MAPT 4029/4885ALDH1A1 40/4885TDP1 2289/4885 |
| US-20090203779-A1 | ESTERS OF LONG-CHAIN ALCOHOLS AND PREPARATION THEREOF | ADH1A, ADH1C, ADH5 | MAPT 2336/4885ALDH1A1 7/4885TDP1 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.