Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 5/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 5/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18504540 | 0.80 | FAAH (0.36) | DAOTSHRALDH1A1FAAHCA1 | |
| SCHEMBL9729023 | 0.80 | BCL2 (0.36) | FAAHLMNAPTGS1MGLL | |
| SCHEMBL8977225 | 0.77 | ALDH1A1 (0.39) | DAODPP4TSHRALDH1A1ALOX15 | |
| SCHEMBL9728529 | 0.75 | XIAP (0.36) | ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8600146 | 0.74 | HCAR1 (0.37) | DAO | |
| SCHEMBL8910664 | 0.74 | FEN1 (0.37) | ALDH1A1LMNAMGLL | |
| SCHEMBL18504537 | 0.73 | CTSK (0.42) | ALDH1A1ALOX15CA1CA2CYP3A4 | |
| SCHEMBL5906077 | 0.71 | TDP1 (0.51) | ALDH1A1LMNAPTGS1MGLL | |
| SCHEMBL8598961 | 0.71 | MAPK11 (0.39) | DAOTSHRALDH1A1ALOX15LMNA | |
| SCHEMBL8917531 | 0.71 | ALDH1A1 (0.34) | DAOTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138068-A | Pesticide | CIBA-GEIGY CORPORATION (US) | 1992-08-11 | — | — | US | disclosed |
| US-5066667-A | Controlling insects and arachnids | CIBA-GEIGY CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0406163-A1 | Thioxotetrazolines | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | disclosed |