Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 4/20 | 0.34 |
| ▸ | THRA | P10827 | 3/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729023 | 0.84 | BCL2 (0.36) | THRB | |
| SCHEMBL9728690 | 0.81 | XIAP (0.35) | XIAPNPBWR1MCHR1KCNH2MAPK8 | |
| SCHEMBL31544426 | 0.77 | MGLL (0.43) | XIAPKCNH2HTR2ASLC6A4CYP2C9 | |
| SCHEMBL9728104 | 0.75 | DAO (0.40) | ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL12114356 | 0.72 | MAPK11 (0.37) | MAPK14ALDH1A1HTT | |
| SCHEMBL9702388 | 0.71 | XIAP (0.45) | XIAPTHRBKCNH2HTR2ASLC6A4 | |
| SCHEMBL8600146 | 0.70 | HCAR1 (0.37) | MAPK14 | |
| SCHEMBL9297258 | 0.70 | NPBWR1 (0.37) | THRBTHRANPBWR1MCHR1CYP2C9 | |
| SCHEMBL9701890 | 0.68 | XIAP (0.40) | XIAPTHRBTHRAKCNH2MAPK14 | |
| SCHEMBL8598961 | 0.67 | MAPK11 (0.39) | MAPK14ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138068-A | Pesticide | CIBA-GEIGY CORPORATION (US) | 1992-08-11 | — | — | US | claimed |