Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9338353 | 0.81 | L3MBTL1 (0.37) | MAPTATMCA12CA1CA2 | |
| SCHEMBL9339655 | 0.80 | TSHR (0.39) | MAPTGAAHTTALDH1A1PKM | |
| SCHEMBL9337958 | 0.77 | MAPT (0.40) | MAPTCA9GAAHTTALDH1A1 | |
| SCHEMBL9339658 | 0.76 | ALDH1A1 (0.33) | ATMALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL9729169 | 0.69 | ALDH1A1 (0.36) | MAPTATMCA12CA1CA2 | |
| SCHEMBL7212713 | 0.69 | ACHE (0.45) | MAPTATMCA9TDP1HTT | |
| SCHEMBL9338356 | 0.65 | KDM4E (0.37) | MAPTATMCA12CA1CA2 | |
| SCHEMBL11014096 | 0.65 | L3MBTL1 (0.38) | MAPTALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL8563574 | 0.61 | MAPT (0.44) | MAPTCA9ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL9337972 | 0.61 | MAPT (0.41) | MAPTCA9GAAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143938-A | PROPANAMINES, THEIR PHARMACOLOGICAL PROPERTIES AND THEIR APPLICATION FOR THERAPEUTIC IN PARTICULAR ANTIDIARRHEAL, PURPOSES | JOUVEINAL S.A. (FR) | 1992-09-01 | — | — | US | disclosed |