Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15916219 | 0.82 | POLB (0.69) | POLBFKBP1ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL29053021 | 0.74 | HTT (0.48) | POLBCYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL6871740 | 0.71 | LMNA (0.47) | POLBMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL2770878 | 0.71 | ALDH1A1 (0.53) | POLBMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27304033 | 0.70 | ALDH1A1 (0.47) | POLBCYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL14005042 | 0.70 | SMN1; SMN2 (1.00) | FKBP1AMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL9729249 | 0.69 | SMN1; SMN2 (0.61) | POLBFKBP1AMEN1KMT2ANPSR1 | |
| SCHEMBL9424119 | 0.69 | LMNA (0.62) | POLBCYP1A2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6037483 | 0.68 | FKBP1A (0.58) | POLBFKBP1AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4461642 | 0.68 | L3MBTL1 (0.53) | POLBCYP1A2CYP3A4CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |