Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446213 | 0.87 | LMNA (0.65) | LMNAALDH1A1L3MBTL1GFERSMN1; SMN2 | |
| SCHEMBL9526741 | 0.79 | LMNA (0.43) | LMNAALDH1A1L3MBTL1GFERSMN1; SMN2 | |
| SCHEMBL12376698 | 0.79 | POLB (0.61) | ALDH1A1L3MBTL1GFERSMN1; SMN2HPGD | |
| SCHEMBL10458833 | 0.78 | LMNA (0.45) | LMNAALDH1A1L3MBTL1GFERSMN1; SMN2 | |
| SCHEMBL9240927 | 0.76 | GAA (0.38) | LMNAALDH1A1L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL9199700 | 0.72 | POLB (0.45) | LMNAALDH1A1L3MBTL1HPGDKDM4E | |
| SCHEMBL9199739 | 0.71 | HTT (0.50) | LMNAALDH1A1L3MBTL1HPGDHTT | |
| SCHEMBL3657281 | 0.71 | TRPA1 (0.42) | LMNAALDH1A1L3MBTL1KDM4EKMT2A | |
| SCHEMBL21806565 | 0.70 | HCAR2 (0.36) | LMNAALDH1A1L3MBTL1GFERHTT | |
| SCHEMBL23135525 | 0.69 | PKM (0.44) | LMNAALDH1A1SMN1; SMN2HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5080708-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1992-01-14 | — | — | US | disclosed |