Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | VHL | P40337 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526216 | 0.80 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1SMN1; SMN2HTTKDM4E | |
| SCHEMBL9729578 | 0.79 | LMNA (0.55) | LMNAALDH1A1L3MBTL1GFERSMN1; SMN2 | |
| SCHEMBL9199703 | 0.77 | POLB (0.37) | L3MBTL1HTTGAAMEN1KMT2A | |
| SCHEMBL10458833 | 0.74 | LMNA (0.45) | LMNAALDH1A1L3MBTL1GFERSMN1; SMN2 | |
| SCHEMBL7030589 | 0.73 | ALDH1A1 (0.33) | LMNAALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL9446213 | 0.73 | LMNA (0.65) | LMNAALDH1A1L3MBTL1GFERSMN1; SMN2 | |
| SCHEMBL3417324 | 0.72 | GAA (0.37) | LMNAALDH1A1L3MBTL1HTTGAA | |
| SCHEMBL9205871 | 0.72 | HPGD (0.40) | ALDH1A1L3MBTL1SMN1; SMN2HPGDHTT | |
| SCHEMBL9527355 | 0.71 | POLB (0.34) | ALDH1A1L3MBTL1SMN1; SMN2HPGDMAPT | |
| SCHEMBL11242567 | 0.69 | L3MBTL1 (0.34) | ALDH1A1L3MBTL1SMN1; SMN2HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337263-B1 | ISOXAZOL(ISOTHIAZOLS)-5-CARBOXAMIDES | BASF Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | disclosed |
| EP-0337263-A2 | Isoxazol(isothiazols)-5-carboxamides | BASF Aktiengesellschaft (DE) | 1989-10-18 | — | — | EP | disclosed |