Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.67 |
| ▸ | MAOB | P27338 | 11/20 | 0.47 |
| ▸ | MAOA | P21397 | 5/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL9730285 | 0.95 | ALOX5 (0.67) | ALOX5MAOBMAOAMTNR1AMEN1 | |
| SCHEMBL9729866 | 0.87 | ALOX5 (0.63) | ALOX5MAOBMAOAMTNR1A | |
| Formamide SCHEMBL9729701 | 0.83 | ALOX5 (0.62) | ALOX5MAOBMAOAMTNR1A | |
| SCHEMBL9730281 | 0.80 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9729591 | 0.78 | ALOX5 (0.61) | ALOX5MAOBMAOAMEN1NPC1 | |
| Formamide SCHEMBL9729640 | 0.75 | ALDH1A1 (0.53) | ALOX5MTNR1AKMT2A | |
| Hydrochloric Acid SCHEMBL9729584 | 0.75 | MTNR1A (0.73) | ALOX5MAOBMTNR1AMEN1KMT2A | |
| SCHEMBL12440576 | 0.75 | ALOX5 (0.52) | ALOX5MAOBMAOA | |
| SCHEMBL9729814 | 0.75 | ALOX5 (0.65) | ALOX5MAOBMAOAMTNR1A | |
| SCHEMBL9730115 | 0.73 | ALOX5 (0.64) | ALOX5MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |