Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729380 | 0.90 | RAB9A (0.42) | POLBKMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL9730614 | 0.71 | KMT2A (0.43) | KMT2ARAB9ANPC1ALDH1A1NFKB1 | |
| SCHEMBL9730768 | 0.69 | RORC (0.41) | P2RX7POLBJAK2RORCKMT2A | |
| SCHEMBL9729554 | 0.68 | IDO1 (0.42) | P2RX7POLBRORCKMT2ANAMPT | |
| SCHEMBL7269217 | 0.66 | POLB (0.47) | POLBKMT2AALDH1A1 | |
| SCHEMBL9730198 | 0.64 | IDO1 (0.37) | P2RX7POLBRORCKMT2ANAMPT | |
| SCHEMBL9729505 | 0.63 | KMT2A (0.47) | KMT2ARAB9ANPC1ALDH1A1NFKB1 | |
| SCHEMBL9729153 | 0.63 | IDO1 (0.39) | P2RX7POLBRORCKMT2ANAMPT | |
| SCHEMBL884676 | 0.63 | KCNA5 (0.57) | POLBCNR1CNR2 | |
| SCHEMBL9853671 | 0.62 | CYP19A1 (0.40) | POLBRAB9ANPC1ALDH1A1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171354-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |