Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ADK | P55263 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731571 | 0.83 | LMNA (0.50) | LMNA | |
| SCHEMBL9729927 | 0.77 | MEN1 (0.60) | KDM4EMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL207751 | 0.74 | CYP1A2 (0.41) | KDM4EKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL12497703 | 0.74 | HRH4 (0.57) | KDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL15114915 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11981553 | 0.73 | SMN1; SMN2 (0.50) | KDM4ESMN1; SMN2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL7588700 | 0.72 | SORD (0.68) | SORDKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28217397 | 0.72 | SMN1; SMN2 (0.53) | KDM4EMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL16091229 | 0.72 | CYP1A2 (0.41) | KDM4ESMN1; SMN2L3MBTL1ALDH1A1MAPT | |
| SCHEMBL13149496 | 0.72 | KDM4E (0.68) | SORDKDM4EMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138058-A | Diabetic screening | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |
| EP-0384370-A1 | Substituted pyrimidine derivatives, process for their preparation, and their use as tool | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | disclosed |