Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 16/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730659 | 0.88 | SIRT1 (0.38) | SIRT1SIRT2RECQLMTNR1AMTNR1B | |
| SCHEMBL9643988 | 0.81 | MTNR1A (0.33) | SIRT1SIRT2RECQLMTNR1AMTNR1B | |
| SCHEMBL9644376 | 0.76 | MTNR1A (0.33) | MTNR1AMTNR1B | |
| SCHEMBL7741198 | 0.76 | SIRT1 (0.43) | SIRT1SIRT2RECQLMTNR1AMTNR1B | |
| SCHEMBL13960994 | 0.68 | SIRT1 (0.57) | SIRT1SIRT2RECQLSIRT3 | |
| SCHEMBL4725031 | 0.68 | SIRT1 (0.63) | SIRT1SIRT2RECQLSIRT3 | |
| SCHEMBL13960992 | 0.66 | SIRT1 (0.59) | SIRT1SIRT2RECQLSIRT3 | |
| SCHEMBL13960223 | 0.66 | SIRT1 (0.59) | SIRT1SIRT2RECQLSIRT3 | |
| SCHEMBL14915072 | 0.64 | TRPM8 (0.46) | SIRT1SIRT2 | |
| SCHEMBL9729760 | 0.64 | MTNR1A (0.35) | SIRT1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079258-A | Enzyme inhibitors, antiallergens treatment of asthma | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-07 | — | — | US | disclosed |