Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729975 | 0.88 | SIRT1 (0.43) | SIRT1MTNR1AMTNR1BRECQLSIRT2 | |
| SCHEMBL9643988 | 0.78 | MTNR1A (0.33) | SIRT1MTNR1AMTNR1BRECQLSIRT2 | |
| SCHEMBL9729760 | 0.76 | MTNR1A (0.35) | SIRT1MTNR1AMTNR1BKDM4EPOLB | |
| SCHEMBL9644376 | 0.75 | MTNR1A (0.33) | MTNR1AMTNR1B | |
| SCHEMBL7741198 | 0.64 | SIRT1 (0.43) | SIRT1MTNR1AMTNR1BRECQLSIRT2 | |
| SCHEMBL24482365 | 0.63 | TRPM8 (0.44) | — | |
| SCHEMBL15546942 | 0.62 | PKM (0.39) | KDM4EMAPT | |
| SCHEMBL3671656 | 0.62 | SIRT1 (0.85) | SIRT1KDM4EMAPTRECQLSIRT2 | |
| SCHEMBL4895997 | 0.62 | SIRT1 (0.44) | SIRT1AR | |
| SCHEMBL4916175 | 0.60 | KDM4E (0.50) | KDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079258-A | Enzyme inhibitors, antiallergens treatment of asthma | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-07 | — | — | US | disclosed |