Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 3/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730122 | 0.88 | GRIN2D (0.41) | HCAR1TLR8 | |
| SCHEMBL10369675 | 0.86 | HSP90AA1 (0.40) | TLR8 | |
| SCHEMBL9730624 | 0.82 | ALDH1A1 (0.44) | — | |
| SCHEMBL8977258 | 0.82 | MAPT (0.44) | NOTUMTLR8 | |
| SCHEMBL8599860 | 0.81 | TLR8 (0.49) | HCAR1NOTUMTLR8 | |
| SCHEMBL1943803 | 0.78 | MEN1 (0.39) | TLR8 | |
| SCHEMBL12892323 | 0.78 | NOTUM (0.38) | HCAR1NOTUM | |
| SCHEMBL5905865 | 0.76 | MGLL (0.43) | HCAR1 | |
| SCHEMBL18504514 | 0.76 | ERCC5 (0.33) | HCAR1 | |
| SCHEMBL9730064 | 0.76 | PPOX (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5136868-A | HERBICIDAL 1-ARYL-4-SUBSTITUTED-1,4-DIHYDRO-5H-TETRAZOL-5-ONES AND SULFUR ANALOGS THEREOF | FMC CORPORATION (US) | 1992-08-11 | — | — | US | disclosed |
| EP-0161304-B1 | HERBICIDAL 1-ARYL-4-SUBSTITUTED-1,4-DIHYDRO-5H-TETRAZOL-5-ONES AND SULFUR ANALOGS THEREOF | FMC Corporation (US) | 1990-01-10 | — | — | EP | disclosed |
| EP-0161304-A4 | HERBICIDAL 1-ARYL-4-SUBSTITUTED-1,4-DIHYDRO-5H-TETRAZOL-5-ONES AND SULFUR ANALOGS THEREOF. | FMC CORP (US) | 1986-04-15 | — | — | EP | disclosed |
| EP-0161304-A1 | HERBICIDAL 1-ARYL-4-SUBSTITUTED-1,4-DIHYDRO-5H-TETRAZOL-5-ONES AND SULFUR ANALOGS THEREOF. | FMC CORP (US) | 1985-11-21 | — | — | EP | disclosed |
| WO-1985001939-A1 | HERBICIDAL 1-ARYL-4-SUBSTITUTED-1,4-DIHYDRO-5H-TETRAZOL-5-ONES AND SULFUR ANALOGS THEREOF | FMC CORPORATION (US) | 1985-05-09 | — | — | WO | disclosed |