Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11321849 | 0.78 | CES1 (0.52) | CES1CES2AKR1B1RENTRPM8 | |
| SCHEMBL8770354 | 0.78 | CTSS (0.41) | MCL1CES1CES2MEN1KMT2A | |
| SCHEMBL8458100 | 0.77 | NPC1 (0.51) | CES1CES2AKR1B1RENTRPM8 | |
| SCHEMBL11680944 | 0.77 | ALOX5 (0.49) | CES1CES2AKR1B1RENTRPM8 | |
| SCHEMBL9847678 | 0.76 | SMN1; SMN2 (0.48) | TRPM8FFAR1MEN1KMT2AALOX5 | |
| SCHEMBL9061013 | 0.75 | CES2 (0.48) | CES1CES2AKR1B1RENTRPM8 | |
| SCHEMBL1529438 | 0.74 | MCL1 (0.55) | MCL1CES1CES2AKR1B1FFAR1 | |
| SCHEMBL8749389 | 0.74 | POLB (0.51) | MCL1RENCTSLCTSBCTSS | |
| SCHEMBL10615657 | 0.73 | CES1 (0.50) | CES1CES2AKR1B1RENTRPM8 | |
| SCHEMBL29291237 | 0.72 | CES1 (0.54) | CES1CES2AKR1B1RENTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5101028-A | Intermediates for dyes | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |