Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27470447 | 0.90 | MEN1 (0.48) | ALOX5CES2CES1MEN1KMT2A | |
| SCHEMBL11321849 | 0.82 | CES1 (0.52) | ALOX5CES2CES1AKR1B1REN | |
| SCHEMBL8458100 | 0.81 | NPC1 (0.51) | ALOX5CES2CES1AKR1B1REN | |
| SCHEMBL9061013 | 0.79 | CES2 (0.48) | ALOX5CES2CES1AKR1B1REN | |
| SCHEMBL9730640 | 0.77 | MCL1 (0.46) | ALOX5CES2CES1AKR1B1REN | |
| SCHEMBL29291237 | 0.76 | CES1 (0.54) | ALOX5CES2CES1AKR1B1REN | |
| SCHEMBL8711613 | 0.76 | ALOX5 (0.47) | ALOX5CES2CES1AKR1B1PAM | |
| SCHEMBL9000284 | 0.76 | HSD17B3 (0.50) | MEN1KMT2A | |
| SCHEMBL815273 | 0.76 | L3MBTL1 (0.48) | ALOX5CES2CES1MAPT | |
| SCHEMBL4430452 | 0.75 | CES2 (0.52) | ALOX5CES2CES1AKR1B1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4038247-A | STABILIZING POLYOLEFINS WITH DIACYL DIHYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1977-07-26 | — | — | US | disclosed |
| US-4002680-A | Process for the manufacture of acylhydrazines | CIBA-GEIGY CORPORATION (US) | 1977-01-11 | — | — | US | disclosed |