Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 14/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 10/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9581996 | 0.91 | HCAR1 (0.40) | HCAR1SCN9ASCN5AELANEP2RX3 | |
| SCHEMBL9730834 | 0.84 | ESR2 (0.33) | ELANE | |
| SCHEMBL9732039 | 0.80 | ESR2 (0.31) | SCN9ASCN5A | |
| SCHEMBL9730517 | 0.79 | DDR1 (0.31) | — | |
| SCHEMBL9582023 | 0.79 | GABRA2 (0.36) | — | |
| SCHEMBL9730727 | 0.75 | KDM5B (0.35) | ELANE | |
| SCHEMBL9765831 | 0.74 | KDM4E (0.41) | — | |
| SCHEMBL9765847 | 0.72 | GAA (0.39) | — | |
| SCHEMBL9581479 | 0.71 | ESR2 (0.32) | SCN9ASCN5AELANE | |
| SCHEMBL7085889 | 0.70 | TRPV4 (0.37) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5109004-A | Cyano phenyl-substituted with heterocylic compound; insecticides, miticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-28 | — | — | US | disclosed |
| EP-0398499-A2 | Insecticides | ZENECA LIMITED (GB) | 1990-11-22 | — | — | EP | disclosed |