Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | CPN1 | P15169 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6755743 | 0.84 | CES2 (0.67) | L3MBTL1TDP1PBRM1CPN1CPB2 | |
| SCHEMBL2927912 | 0.80 | L3MBTL1 (1.00) | L3MBTL1TDP1PTPN1LMNACES2 | |
| SCHEMBL6755738 | 0.79 | LMNA (0.69) | L3MBTL1TDP1PBRM1CPN1CPB2 | |
| SCHEMBL9254112 | 0.76 | PBRM1 (0.55) | PBRM1LMNANPC1MITFPOLB | |
| SCHEMBL21200752 | 0.76 | ACHE (0.56) | TDP1PBRM1CPN1CPB2LMNA | |
| SCHEMBL16781991 | 0.75 | L3MBTL1 (0.71) | L3MBTL1TDP1PTPN1LMNACES2 | |
| SCHEMBL15209808 | 0.75 | PBRM1 (0.70) | L3MBTL1TDP1PBRM1LMNACES2 | |
| SCHEMBL147608 | 0.75 | PBRM1 (1.00) | L3MBTL1TDP1PBRM1LMNANPC1 | |
| Biphenyl SCHEMBL28656314 | 0.75 | L3MBTL1 (0.87) | L3MBTL1TDP1PTPN1LMNACES2 | |
| 3-Aminobenzoic Acid SCHEMBL28231735 | 0.75 | PBRM1 (0.70) | L3MBTL1TDP1PBRM1LMNACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153208-A | Influence metabolism of collagen or biosynthesis of c/q/ | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-06 | — | — | US | disclosed |
| US-5130317-A | Immunosuppressants and fibrosuppressants for metabolism of collagen | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-14 | — | — | US | disclosed |
| US-5082598-A | Thermosetting unsaturated ester, thiuram compound, crosslinking agent, copper compound | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |