Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584018 | 0.80 | PLA2G2A (0.61) | PLA2G2AALDH1A1LMNABCHEHTR6 | |
| SCHEMBL28239560 | 0.76 | POLB (0.60) | POLBL3MBTL1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9732943 | 0.76 | ALDH1A1 (0.47) | POLBP2RX7ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28524187 | 0.74 | LTB4R (0.57) | POLBL3MBTL1PLA2G2AALDH1A1LMNA | |
| SCHEMBL9732936 | 0.73 | MAPT (0.54) | POLBALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL5409497 | 0.73 | MEN1 (0.42) | ALDH1A1MEN1KMT2AHTR6 | |
| SCHEMBL797463 | 0.72 | ALDH1A1 (0.69) | POLBL3MBTL1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9733117 | 0.72 | ALDH1A1 (0.67) | POLBL3MBTL1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9732575 | 0.71 | ALDH1A1 (0.49) | POLBP2RX7PLA2G2AALDH1A1LMNA | |
| SCHEMBL9732913 | 0.71 | LTB4R (0.59) | POLBPLA2G2AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007829-A1 | INDOLE-3-METHANAMINES USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |