Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 2/20 | 0.50 |
| ▸ | OXTR | P30559 | 2/20 | 0.50 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9354245 | 0.84 | OXTR (0.48) | RBP4OXTRAVPR1APDE4BKIF11 | |
| SCHEMBL9450748 | 0.83 | RBP4 (0.51) | RBP4OXTRAVPR1AHPGDALOX12 | |
| SCHEMBL9450896 | 0.82 | RBP4 (0.50) | RBP4PDE4BHPGDALOX12SMN1; SMN2 | |
| SCHEMBL9450847 | 0.81 | RBP4 (0.50) | RBP4PDE4BKMT2ADPP4HPGD | |
| SCHEMBL2299437 | 0.79 | RBP4 (0.54) | RBP4PDE4BKMT2AMEN1ALDH1A1 | |
| SCHEMBL15641025 | 0.73 | RBP4 (0.45) | RBP4HPGDALOX12SMN1; SMN2RORC | |
| SCHEMBL15641024 | 0.73 | RBP4 (0.45) | RBP4HPGDALOX12SMN1; SMN2RORC | |
| SCHEMBL29277465 | 0.73 | SLC6A4 (0.43) | RBP4MAPTFPR2PROKR1 | |
| SCHEMBL9903720 | 0.72 | HRH1 (0.53) | KMT2ACYP2C9SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9450889 | 0.72 | KIF11 (0.40) | OXTRAVPR1ARORCKIF11KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126344-A | Angiotensin antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-30 | — | — | US | disclosed |
| US-5095014-A | 3-(2-chloro-4-(trifluoromethyl)phenoxy)-1-azetidine carboxamides having anticonvulsant activity | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-03-10 | — | — | US | disclosed |
| WO-1991007404-A1 | DIAZINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-30 | — | — | WO | disclosed |